RUNX1 Polyclonal AntibodyE-AB-11848
Product Type: Antibody
Descritpion: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Neuroscience, Stem cells
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Immunogen: Synthetic peptide of human RUNX1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 51kDa
Tissue Specificity/Positive Control: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-runx1_polyclonal_antibody-39867.html
Manual Link: https://www.elabscience.com/viewpdf-39867-elabscience-E-AB-11848.PDF