PLCG1 Polyclonal AntibodyE-AB-12075
Product Type: Antibody
Descritpion: Plays a role in actin reorganization and cell migration. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.
Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Immunogen: Synthetic peptide of human PLCG1 (Ab-783)
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 149kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cell projection>lamellipodium. Cell projection>ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-plcg1_polyclonal_antibody-39916.html
Manual Link: https://www.elabscience.com/viewpdf-39916-elabscience-E-AB-12075.PDF