Product Type: Antibody
Descritpion: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience
Recommended Dilutions: WB 1:500-1:1000, IHC 1:50-100, IF/ICC 1:100-1:200
Size: 200 uL
Immunogen: Synthetic peptide of human NOS3 (Ab-1177)
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 140kDa
Tissue Specificity/Positive Control: Platelets, placenta, liver and kidney.
Cellular Localization: Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle and which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-nos3_polyclonal_antibody-39927.html
Manual Link: https://www.elabscience.com/viewpdf-39927-elabscience-E-AB-12086.PDF