PLCG2 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction
Applications: WB,IF
Recommended Dilutions: WB 1:500-1:1000, IHC 1:50-100, IF/ICC 1:100-1:200
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P16885
Gene Accession:
Reactivity: Human
,Mouse
,Rat

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human PLCG2 (Ab-753)
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 148kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytosol,Extracellular region or secreted,extracellular exosome,Plasma Membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-plcg2_polyclonal_antibody-39929.html
Manual Link: https://www.elabscience.com/viewpdf-39929-elabscience-E-AB-12088.PDF