MAP1LC3A Polyclonal AntibodyE-AB-12116
Product Type: Antibody
Descritpion: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction
Recommended Dilutions: WB 1:500-1:1000
Size: 200 uL
Immunogen: Synthetic peptide of human MAP1LC3A
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 14kDa
Tissue Specificity/Positive Control: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
Cellular Localization: Cytoplasm>cytoskeleton. Endomembrane system. Cytoplasmic vesicle>autophagosome membrane. LC3-II binds to the autophagic membranes.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-map1lc3a_polyclonal_antibody-39957.html
Manual Link: https://www.elabscience.com/viewpdf-39957-elabscience-E-AB-12116.PDF