ABCG2 Polyclonal AntibodyE-AB-12132
Product Type: Antibody
Descritpion: Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Research Areas: Cancer, Metabolism, Signal transduction, Stem cells, Tags & Cell Markers
Recommended Dilutions: WB 1:500-1:1000
Size: 200 uL
Immunogen: Synthetic peptide of human ABCG2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 72kDa
Tissue Specificity/Positive Control: Highly expressed in placenta. Low expression in small intestine, liver and colon.
Cellular Localization: Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-abcg2_polyclonal_antibody-39973.html
Manual Link: https://www.elabscience.com/viewpdf-39973-elabscience-E-AB-12132.PDF