SMAD1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
Applications: WB
Recommended Dilutions: WB 1:500-1:1000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: Q15797
Gene Accession:
Reactivity: Human
,Mouse
,Rat

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human SMAD1 (Ab-206)
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 52kDa
Tissue Specificity/Positive Control: Ubiquitous. Highest expression seen in the heart and skeletal muscle.
Cellular Localization: Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-smad1_polyclonal_antibody-39983.html
Manual Link: https://www.elabscience.com/viewpdf-39983-elabscience-E-AB-12142.PDF