TFDP1 Polyclonal AntibodyE-AB-12168
Product Type: Antibody
Descritpion: This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.TFDP1 (Transcription Factor Dp-1) is a Protein Coding gene. Diseases associated with TFDP1 include Retinoblastoma. Among its related pathways are Cellular Senescence and Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription coactivator activity. An important paralog of this gene is TFDP3.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Stem cells
Recommended Dilutions: WB 1:500-1:1000
Size: 200 uL
Immunogen: Synthetic peptide of human TFDP1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 45kDa
Tissue Specificity/Positive Control: Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-tfdp1_polyclonal_antibody-40008.html
Manual Link: https://www.elabscience.com/viewpdf-40008-elabscience-E-AB-12168.PDF