ZDHHC17 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Palmitoyltransferase ZDHHC17 is an enzyme that contains a DHHC domain that in humans is encoded by theZDHHC17 gene. Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. Palmitoylates MPP1 in erythrocytes. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. Has transforming activity. Mediates Mg2+ transport.
Research Areas: Cancer, Neuroscience, Signal transduction
Applications: WB,ELISA
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-100
Size: 200 uL
Concentration: 2mg/mL
Swissprot: Q8IUH5
Gene Accession: NP_056151
Reactivity: Human
,Mouse
,Rat

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human ZDHHC17  
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 73kDa
Tissue Specificity/Positive Control: Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney. ZDHHC17 is the only palmitoyltransferase in erythrocytes.
Cellular Localization: Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-zdhhc17_polyclonal_antibody-40041.html
Manual Link: https://www.elabscience.com/viewpdf-40041-elabscience-E-AB-12201.PDF