Product Type: Antibody
Descritpion: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
Research Areas: Epigenetics and Nuclear Signaling, Developmental biology, Stem cells
Recommended Dilutions: WB 1:200-1:1000, IHC 1:100-300
Size: 200 uL
Gene Accession: NP_003404
Immunogen: Synthetic peptide of human ZIC3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 51kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus. Cytoplasm. Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-zic3_polyclonal_antibody-40051.html
Manual Link: https://www.elabscience.com/viewpdf-40051-elabscience-E-AB-12211.PDF