Product Type: Antibody
Descritpion: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
Research Areas: Signal Transduction
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_001118
Immunogen: Synthetic peptide of human AP1B1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Widely expressed.
Cellular Localization: Cytosol,Golgi apparatus,Golgi apparatus,Golgi membrane,trans-Golgi network membrane,Lysosome,lysosomal membrane,Other locations:clathrin adaptor complex,clathrin-coated endocytic vesicle membrane,cytoplasmic vesicle membrane,intracellular membrane-bounded organelle
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ap1b1_polyclonal_antibody-31702.html
Manual Link: https://www.elabscience.com/viewpdf-31702-elabscience-E-AB-12245.PDF