LOX Polyclonal AntibodyE-AB-12255
Product Type: Antibody
Descritpion: The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Cardiovascular, Signal transduction
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Gene Accession: NP_002308
Immunogen: Synthetic peptide of human LOX
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 47kDa
Tissue Specificity/Positive Control: Heart, placenta, skeletal muscle, kidney, lung and pancreas.
Cellular Localization: Secreted>extracellular space.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-lox_polyclonal_antibody-40054.html
Manual Link: https://www.elabscience.com/viewpdf-40054-elabscience-E-AB-12255.PDF