CCL2 Polyclonal AntibodyE-AB-12307
Product Type: Antibody
Descritpion: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Research Areas: Cancer, Cardiovascular, Metabolism, Immunology
Recommended Dilutions: IHC 1:25-1:50
Size: 200 uL
Gene Accession: NP_002973
Immunogen: Synthetic peptide of human CCL2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level).1 Publication
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ccl2_polyclonal_antibody-31763.html
Manual Link: https://www.elabscience.com/viewpdf-31763-elabscience-E-AB-12307.PDF