Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_001777
Immunogen: Synthetic peptide of human CDK1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 34kDa
Tissue Specificity/Positive Control: Isoform 2 is found in breast cancer tissues.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-cdk1_polyclonal_antibody-31769.html
Manual Link: https://www.elabscience.com/viewpdf-31769-elabscience-E-AB-12313.PDF