Product Type: Antibody
Descritpion: This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
Research Areas: Neuroscience, Signal transduction
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_065168
Immunogen: Synthetic peptide of human GJC2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles.
Cellular Localization: Cell membrane. Cell junction>gap junction.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-connexin_47_polyclonal_antibody-31795.html
Manual Link: https://www.elabscience.com/viewpdf-31795-elabscience-E-AB-12341.PDF