TNFRSF21 Polyclonal AntibodyE-AB-12371
Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Research Areas: Cell Biology
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Gene Accession: NP_055267
Immunogen: Synthetic peptide of human TNFRSF21
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 72kDa
Tissue Specificity/Positive Control: Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-tnfrsf21_polyclonal_antibody-31824.html
Manual Link: https://www.elabscience.com/viewpdf-31824-elabscience-E-AB-12371.PDF