DNM1 Polyclonal AntibodyE-AB-12374
Product Type: Antibody
Descritpion: This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
Research Areas: Cancer, Neuroscience, Signal transduction
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Gene Accession: NP_004399
Immunogen: Synthetic peptide of human DNM1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 98kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm. Cytoplasm>cytoskeleton. Microtubule-associated.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-dnm1_polyclonal_antibody-31827.html
Manual Link: https://www.elabscience.com/viewpdf-31827-elabscience-E-AB-12374.PDF