
EDAR Polyclonal Antibody
E-AB-12381
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Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
Research Areas: Epigenetics and Nuclear Signaling, Signal transduction
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:35-1:150
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: Q9UNE0
Gene Accession: NP_071731
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human EDAR
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Detected in fetal kidney, lung, skin and cultured neonatal epidermal keratinocytes. Not detected in lymphoblast and fibroblast cell lines.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-edar_polyclonal_antibody-31834.html
Manual Link: https://www.elabscience.com/viewpdf-31834-elabscience-E-AB-12381.PDF