Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform.
Research Areas: Cancer, Cardiovascular, Developmental biology, Neuroscience, Signal transduction, Stem cells
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_000132
Immunogen: Synthetic peptide of human FGFR2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Secreted and Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-fgfr2_polyclonal_antibody-31857.html
Manual Link: https://www.elabscience.com/viewpdf-31857-elabscience-E-AB-12405.PDF