FPR2 Polyclonal AntibodyE-AB-12412
Product Type: Antibody
Descritpion: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4
Research Areas: Cancer, Cardiovascular, Signal transduction
Recommended Dilutions: IHC 1:20-1:100
Size: 200 uL
Gene Accession: NP_001453
Immunogen: Synthetic peptide of human FPR2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.
Cellular Localization: Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-fpr2_polyclonal_antibody-31864.html
Manual Link: https://www.elabscience.com/viewpdf-31864-elabscience-E-AB-12412.PDF