FOXA2 Polyclonal AntibodyE-AB-12417
Product Type: Antibody
Descritpion: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Developmental biology, Stem cells
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Gene Accession: NP_710141
Immunogen: Synthetic peptide of human FOXA2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 48kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner and in response to insulin signaling via AKT1 is exported from the nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-foxa2_polyclonal_antibody-31869.html
Manual Link: https://www.elabscience.com/viewpdf-31869-elabscience-E-AB-12417.PDF