SUMO2/3/4 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Research Areas: Cell Biology
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300
Size: 200 uL
Concentration: 0.4mg/mL
Swissprot: P61956,P55854,Q6EEV6
Gene Accession: NP_008868/NP_008867/NP_001002255
Reactivity: Human
,Mouse

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human SUMO2/SUMO3/SUMO4
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 12kDa
Tissue Specificity/Positive Control:
Cellular Localization: Extracellular region or secreted,extracellular exosome,Nucleus,nucleoplasm,nucleus,PML body,Other locations:cytoplasm,kinetochore
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-sumo2_3_4_polyclonal_antibody-40059.html
Manual Link: https://www.elabscience.com/viewpdf-40059-elabscience-E-AB-12439.PDF