CSF3R Polyclonal AntibodyE-AB-12465
Product Type: Antibody
Descritpion: The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
Research Areas: Cancer, Immunology, Stem cells
Recommended Dilutions: IHC 1:15-1:50
Size: 200 uL
Gene Accession: NP_000751
Immunogen: Synthetic peptide of human CSF3R
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta.
Cellular Localization: Secreted and Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-csf3r_polyclonal_antibody-31916.html
Manual Link: https://www.elabscience.com/viewpdf-31916-elabscience-E-AB-12465.PDF