GHSR Polyclonal AntibodyE-AB-12471
Product Type: Antibody
Descritpion: This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Research Areas: Cancer, Metabolism, Neuroscience
Recommended Dilutions: WB 1:1000-1:3000
Size: 200 uL
Gene Accession: NP_004113
Immunogen: Synthetic peptide of human GHSR
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 41kDa
Tissue Specificity/Positive Control: Pituitary and hypothalamus.
Cellular Localization: Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ghsr_polyclonal_antibody-31922.html
Manual Link: https://www.elabscience.com/viewpdf-31922-elabscience-E-AB-12471.PDF