HDAC1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem cells
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:25-1:100
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: Q13547
Gene Accession: NP_004955
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human HDAC1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 55kDa
Tissue Specificity/Positive Control: Ubiquitous, with higher levels in heart, pancreas and testis, and lower levels in kidney and brain.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-hdac1_polyclonal_antibody-31949.html
Manual Link: https://www.elabscience.com/viewpdf-31949-elabscience-E-AB-12500.PDF