Product Type: Antibody
Descritpion: This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating witHuman, Mouseany different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem cells
Recommended Dilutions: IHC 1:15-1:50
Size: 200 uL
Gene Accession: NP_001518
Immunogen: Synthetic peptide of human HDAC2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Widely expressed; lower levels in brain and lung.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-hdac2_polyclonal_antibody-31950.html
Manual Link: https://www.elabscience.com/viewpdf-31950-elabscience-E-AB-12501.PDF