Product Type: Antibody
Descritpion: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
Research Areas: Cancer, Cell Biology, Signal transduction
Recommended Dilutions: WB 1:1000-1:5000, IHC 1:100-1:300
Size: 200 uL
Gene Accession: NP_036559
Immunogen: Synthetic peptide of human KLK5
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 32kDa
Tissue Specificity/Positive Control: Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin.
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-klk5_polyclonal_antibody-31973.html
Manual Link: https://www.elabscience.com/viewpdf-31973-elabscience-E-AB-12528.PDF