MTOR Polyclonal AntibodyE-AB-12581
Product Type: Antibody
Descritpion: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_004949
Immunogen: Synthetic peptide of human MTOR
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in numerous tissues, with highest levels in testis.
Cellular Localization: Endoplasmic reticulum membrane. Golgi apparatus membrane. Mitochondrion outer membrane. Lysosome. Cytoplasm. Nucleus>PML body. Shuttles between cytoplasm and nucleus. Accumulates in the nucleus in response to hypoxia (By similarity). Targeting to lysosomes depends on amino acid availability and RRAGA and RRAGB.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-mtor_polyclonal_antibody-32026.html
Manual Link: https://www.elabscience.com/viewpdf-32026-elabscience-E-AB-12581.PDF