Product Type: Antibody
Descritpion: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Research Areas: Cancer, Metabolism, Signal transduction
Recommended Dilutions: WB 1:200-1:1000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_002602
Immunogen: Synthetic peptide of human PDK2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 46kDa
Tissue Specificity/Positive Control: Expressed in many tissues, with the highest level in heart and skeletal muscle, intermediate levels in brain, kidney, pancreas and liver, and low levels in placenta and lung.
Cellular Localization: Mitochondrion matrix.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pdk2_polyclonal_antibody-32062.html
Manual Link: https://www.elabscience.com/viewpdf-32062-elabscience-E-AB-12618.PDF