Product Type: Antibody
Descritpion: Neutral amino acid transporter A is a protein that in humans is encoded by the SLC1A4 gene. In melanocytic cells SLC1A4 gene expression may be regulated by MITF. ASCT1 does not transport glutamate or aspartate but alanine, serine, cysteine, and threonine instead. ASCT1 transporter functions primarily as an amino acid exchanger. Transport is associated with a chloride channel activity that is thermodynamically uncoupled from amino acid transport.
Research Areas: Metabolism, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_003029
Immunogen: Synthetic peptide of human SLC1A4
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 56kDa
Tissue Specificity/Positive Control: Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined.
Cellular Localization: Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-slc1a4_polyclonal_antibody-32085.html
Manual Link: https://www.elabscience.com/viewpdf-32085-elabscience-E-AB-12641.PDF