TERF2 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Concentration: 0.1mg/mL
Swissprot: Q15554
Gene Accession: NP_005643.2
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human TERF2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes.
Cellular Localization: Nucleus. Chromosome>telomere. Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-terf2_polyclonal_antibody-32111.html
Manual Link: https://www.elabscience.com/viewpdf-32111-elabscience-E-AB-12667.PDF