Product Type: Antibody
Descritpion: This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
Research Areas: Cardiovascular, Metabolism, Neuroscience, Signal transduction
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_001129
Immunogen: Synthetic peptide of human AGRP
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
Cellular Localization: Secreted. Golgi apparatus lumen.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-agrp_polyclonal_antibody-32149.html
Manual Link: https://www.elabscience.com/viewpdf-32149-elabscience-E-AB-12705.PDF