AKR1B1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. 
Research Areas: Cancer, Metabolism, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:50-1:200
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: P15121
Gene Accession: NP_001619
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human AKR1B1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 36kDa
Tissue Specificity/Positive Control: Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-akr1b1_polyclonal_antibody-32153.html
Manual Link: https://www.elabscience.com/viewpdf-32153-elabscience-E-AB-12709.PDF