SLC8A3 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
Research Areas: Metabolism, Signal transduction
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:100-1:300
Size: 200 uL
Concentration: 0.5mg/mL
Swissprot: P57103
Gene Accession: NP_001123889
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human SLC8A3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Isoform 2 is expressed in brain and skeletal muscle. Isoform 3 is expressed in excitable cells of brain, retina and skeletal muscle. Isoform 4 is expressed in skeletal muscle.1 Publication
Cellular Localization: Membrane; Multi-pass membrane protein.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-slc8a3_polyclonal_antibody-32241.html
Manual Link: https://www.elabscience.com/viewpdf-32241-elabscience-E-AB-12798.PDF