Product Type: Antibody
Descritpion: Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.
Research Areas: Cancer, Cell Biology, Signal transduction
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_001042.1
Immunogen: Synthetic peptide of human SSTR3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Brain, pituitary and pancreas.
Cellular Localization: Cell membrane. Internalized into endoplasmic vesicles upon somatostatin-stimulation.
Storage: Store at -20C. Avoid freeze / thaw cycles.