Product Type: Antibody
Descritpion: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_001005781
Immunogen: Synthetic peptide of human SUMO1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus membrane. Nucleus speckle. Cytoplasm. Recruited by BCL11A into the nuclear body.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-sumo1_polyclonal_antibody-32333.html
Manual Link: https://www.elabscience.com/viewpdf-32333-elabscience-E-AB-12891.PDF