Product Type: Antibody
Descritpion: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction, Stem cells
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_001124388
Immunogen: Synthetic peptide of human TGFBR1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Found in all tissues examined, most abundant in placenta and least abundant in brain and heart.
Cellular Localization: Cytoplasm
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-tgf_?_receptor_i_polyclonal_antibody-32346.html
Manual Link: https://www.elabscience.com/viewpdf-32346-elabscience-E-AB-12904.PDF