Product Type: Antibody
Descritpion: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Cardiovascular, Metabolism, Immunology, Neuroscience, Signal transduction
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_001597
Immunogen: Synthetic peptide of human ABCA2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Highy expressed in the brain, whereas lower levels of expression is observed in kidney and liver.
Cellular Localization: Endosome. Membrane. Lysosome. Membrane. Forms discrete, punctate intracellular vesicles.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-abca2_polyclonal_antibody-32376.html
Manual Link: https://www.elabscience.com/viewpdf-32376-elabscience-E-AB-12934.PDF