Product Type: Antibody
Descritpion: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_002616
Immunogen: Synthetic peptide of human PFKFB1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Liver.
Cellular Localization: Cytosol,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex,cytosol
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pfkfb1_polyclonal_antibody-32468.html
Manual Link: https://www.elabscience.com/viewpdf-32468-elabscience-E-AB-13026.PDF