PLA2G6 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.
Research Areas: Signal transduction
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:15-1:50
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: O60733
Gene Accession: NP_003551
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human PLA2G6
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Four different transcripts were found to be expressed in a distinct tissue distribution.
Cellular Localization: Cytoplasm and Membrane. Recruited to the membrane-enriched pseudopod upon MCP1/CCL2 stimulation in monocytes.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-pla2g6_polyclonal_antibody-32546.html
Manual Link: https://www.elabscience.com/viewpdf-32546-elabscience-E-AB-13106.PDF