LE/AF Purified Anti-Mouse CD8a Monoclonal Antibody

LE/AF Purified Anti-Mouse CD8a Monoclonal Antibody

E-AB-1317

Regular price $230.00 $202.00 You Pay

Supplier: Elabscience
Product Type: monoclonal antibody for FC
Description: CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked ? and ? chains that form the ?(CD8a)/?(CD8b) heterodimer and ?/? homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 ?/? heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR ?/? T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 ?/? homodimer is expressed on a subset of ?/? TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Resarch Areas: Immunology
Size: 500 ug
Clonality: Monoclonal
Clone No: 53.6.7
Swissprot: P01731
Applications: FCM,IHC,IP
Recommended Usage:
Reactivity: Mouse
Host: Rat
Isotype: Rat IgG2a
Formulation: PBS, PH7.2
Purification: Protein G
Conjugation: Low endotoxin/Azide Free
Storage: Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid freeze/thaw cycles.

Product Link: https://www.elabscience.com/p-le_af_purified_anti_mouse_cd8a_monoclonal_antibody-39195.html
Manual Link: https://www.elabscience.com/viewpdf-39195-elabscience-E-AB-1317.PDF