Product Type: Antibody
Descritpion: Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex.
Research Areas: Signal transduction, Stem cells
Recommended Dilutions: WB 1:200-1:1000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_001257449
Immunogen: Synthetic peptide of human DAAM1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 123kDa
Tissue Specificity/Positive Control: Expressed in all tissues examined.
Cellular Localization: Cytoplasmic. Note: Perinuclear.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-daam1_polyclonal_antibody-32622.html
Manual Link: https://www.elabscience.com/viewpdf-32622-elabscience-E-AB-13182.PDF