Product Type: Antibody
Descritpion: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Research Areas: Cancer, Cell Biology
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_036247
Immunogen: Synthetic peptide of human CASP8AP2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 223kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm. Nucleus. Localizes to discrete nuclear foci.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-casp8ap2_polyclonal_antibody-32686.html
Manual Link: https://www.elabscience.com/viewpdf-32686-elabscience-E-AB-13246.PDF