Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.
Research Areas: Cell Biology, Neuroscience, Signal transduction
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Concentration: 0.7mg/mL
Swissprot: Q9NZ56
Gene Accession: NP_064450
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human FMN2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Expressed almost exclusively in the developing and mature central nervous system.
Cellular Localization: Cytoplasm>cytoskeleton. Cytoplasm>perinuclear region. Cytoplasm>cytosol. Cell membrane. Cytoplasmic vesicle membrane. Cytoplasm>cell cortex. Nucleus>nucleolus. Recruited to the membranes via its interaction with SPIRE1. Colocalizes with the actin cytoskeleton. Detected at the cleavage furrow during asymmetric oocyte division and polar body extrusion.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-fmn2_polyclonal_antibody-32689.html
Manual Link: https://www.elabscience.com/viewpdf-32689-elabscience-E-AB-13249.PDF