LE/AF Purified Anti-Mouse CD45RB Monoclonal AntibodyE-AB-1329
Product Type: monoclonal antibody for FC
Description: CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naïve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.
Resarch Areas: Immunology, Signal transduction, Stem cells
Size: 500 ug
Clone No: HB220
Isotype: Rat IgG2a
Formulation: PBS, PH7.2
Purification: Protein G
Conjugation: Low endotoxin/Azide Free
Storage: Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid freeze/thaw cycles.
Product Link: https://www.elabscience.com/p-le_af_purified_anti_mouse_cd45rb_monoclonal_antibody-39207.html
Manual Link: https://www.elabscience.com/viewpdf-39207-elabscience-E-AB-1329.PDF