LE/AF Purified Anti-Mouse CD49d Monoclonal AntibodyE-AB-1330
Product Type: monoclonal antibody for FC
Description: CD49d is a 150 kD glycoprotein, also known as ?4 integrin or VLA-4 ? chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two ? chains, ?1 (CD29) or ?7, to form the VLA-4 (integrin ?4?1) or LPAM-1 (integrin ?4?7) complexes. CD49d plays a critical role in both adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin. The 9C10(MFR4.B) antibody, in combination with the R1-2 monoclonal antibody, completely blocks VCAM-1 binding to VLA-4.
Resarch Areas: Immunology, Signal Transduction, Cardiovascular, Stem cells
Size: 500 ug
Clone No: PS/2
Isotype: Rat IgG2b
Formulation: PBS, PH7.2
Purification: Protein G
Conjugation: Low endotoxin/Azide Free
Storage: Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid freeze/thaw cycles.
Product Link: https://www.elabscience.com/p-le_af_purified_anti_mouse_cd49d_monoclonal_antibody-39208.html
Manual Link: https://www.elabscience.com/viewpdf-39208-elabscience-E-AB-1330.PDF