LE/AF Purified Anti-Mouse TNFa Monoclonal AntibodyE-AB-1368
Product Type: monoclonal antibody for FC
Description: T-bet, also known as T-box transcription factor T-bet, is considered to be a "master regulator" of Th1 lymphoid development controlling the production of the cytokine IFN-?. T-bet is widely expressed in hematopoietic cells including stem cells, NK cells, B cells, and T cells. T-bet is critical for the control of microbial pathogens, and knockout animals show multiple physiologic and inflammatory features characteristic of asthma. T-bet expression is optimally observed after IL-12 stimulation and can be suppressed by addition of the Th2 cytokine IL-4 or neutralization of IL-12.
Resarch Areas: Cancer, Cardiovascular, Metabolism, Immunology, Signal transduction
Size: 500 ug
Clone No: 4B10
Isotype: Rat IgG1
Formulation: PBS, PH7.2
Purification: Protein G
Conjugation: Low endotoxin/Azide Free
Storage: Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid freeze/thaw cycles.
Product Link: https://www.elabscience.com/p-le_af_purified_anti_mouse_tnf?_monoclonal_antibody-39246.html
Manual Link: https://www.elabscience.com/viewpdf-39246-elabscience-E-AB-1368.PDF