LE/AF Purified Anti-Mouse TNFa Monoclonal AntibodyE-AB-1373
Product Type: monoclonal antibody for FC
Description: TNF-? is secreted by macrophages, monocytes, neutrophils, T-cells (principally CD4+), and NK-cells. Many transformed cell lines also secrete TNF-?. Monomeric mouse TNF-? is 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD protein. TNF-? forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-? has also been described. TNF-? binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.
Resarch Areas: Cancer, Cardiovascular, Metabolism, Immunology, Signal transduction
Size: 500 ug
Clone No: XT3.11
Isotype: Rat IgG1
Formulation: PBS, PH7.2
Purification: Protein G
Conjugation: Low endotoxin/Azide Free
Storage: Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid freeze/thaw cycles.
Product Link: https://www.elabscience.com/p-le_af_purified_anti_mouse_tnf?_monoclonal_antibody-39251.html
Manual Link: https://www.elabscience.com/viewpdf-39251-elabscience-E-AB-1373.PDF