Purified Anti-Human CD8 Monoclonal AntibodyE-AB-1404
Product Type: monoclonal antibody for FC
Description: CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the ?3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Resarch Areas: Immunology, Stem cells
Size: 100 ug
Clone No: HIT8a
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used from 20 µL to 5 µL per 100 µL of peripheral blood. Please check your vial). Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Mouse IgG1
Formulation: PBS with 0.09% NaN3, 0.2% BSA, PH7.2
Storage: Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid freeze/thaw cycles.
Product Link: https://www.elabscience.com/p-purified_anti_human_cd8_monoclonal_antibody-38955.html
Manual Link: https://www.elabscience.com/viewpdf-38955-elabscience-E-AB-1404.PDF