Purified Anti-Human CD86 Monoclonal AntibodyE-AB-1430
Product Type: monoclonal antibody for FC
Description: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Resarch Areas: Cancer, Immunology, Microbiology, Stem cells
Size: 100 ug
Clone No: BU63
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used from 20 µL to 5 µL per 100 µL of peripheral blood. Please check your vial). Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Mouse IgG1
Formulation: PBS with 0.09% NaN3, 0.2% BSA, PH7.2
Storage: Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid freeze/thaw cycles.
Product Link: https://www.elabscience.com/p-purified_anti_human_cd86_monoclonal_antibody-38981.html
Manual Link: https://www.elabscience.com/viewpdf-38981-elabscience-E-AB-1430.PDF